In this episode of OMH Dailies, we'll look at the relationship between COVID-19 and vascular diseases, why Mumbai will see a six-fold increase in heart attack mortality by 2021, and the links between antacids, a common drug that neutralises stomach acid, and cardiovascular disease.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes multi-system dysfunction, and new evidence suggests that SARS-CoV-2-mediated endothelial injury is a key virus effector. Potential therapies that address vascular system dysfunction and its consequences could play a significant role in treating SARS-CoV-2 infection and its long-term consequences.
COVID-19 is well-known for its association with the respiratory system. However, complications such as heart attacks are common in severe Covid-19 patients.
Researchers have been investigating the link between COVID-19 and vascular diseases since the outbreak began. Many studies have found that people with severe COVID-19 are more likely to have strokes, blood clots, and other vascular complications.
Due to 80 percent genomic sequence identity, SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), shares many biological features with SARS-CoV, the virus that causes severe acute respiratory syndrome.
The interaction between the viral spike (S) protein and angiotensin-converting enzyme 2, which causes the virus to enter host cells, is likely to be involved in COVID-19's cardiovascular manifestations.
The existence of underlying cardiovascular comorbidities in COVID-19 patients is associated with a high mortality rate.
COVID-19 has been linked to cardiovascular problems such as myocardial injury, arrhythmias, acute coronary syndrome, and venous thromboembolism.
Several medications used to treat COVID-19 have questionable safety and efficacy profiles.
However, researchers believe that it is the immune system that attacks infected respiratory cells rather than the coronavirus that causes vascular disease. This response can result in inflammation, damage to the lining of your blood vessels, and blood clots.
More research on this topic is needed, but the link between COVID-19 and Vascular Diseases is well established.